I've tried the synthetic weeds, and I'm definitely not a fan.
It tasted like, really bad. And the high was super edgy... It was just like an edgy paranoid high, without any of the fun stuff like regular weed has. Music didn't sound better, food didn't taste good, there was no body buzz, etc. The synthetic stuff only has one Cannabinoid though, where natural has at least 85 known Cannabinoids, so of course you're going to get a much wider range of effects.