There was a spider, and I had to kill the eggs to save everyone else. There were other insects too, I don't think any humans though. We were on an island, very leafy; there was tonnes of trees and greenery but we were in a small clearing. Standing on a moss covered rock. The spider was huge, she didn't mind as I killed her eggs, she could talk. She didn't say anything though, she just watched, and I think I might've Okami Celestial Brush slashed them but without stopping time.
Then they were all grouped and it turns out I didn't have to kill them afterall.